Real-World Evidence Assessment of the Risk of Non-fatal Stroke in Patients Prescribed SGLT2 Inhibitors

Adults with type 2 diabetes prescribed SGLT2 inhibitors had a lower incidence of stroke

AT Ayers, CN Ho, U Masharani, CW Pike, H Magon, ML Jackson, S Gombar, AF Scheideman, MM Shao, DC Klonoff

Stroke Research and Treatment, 2026(1): 6411721 (2026)

Plain-language summary

We used real-world health records to compare the risk of non-fatal stroke in people with type 2 diabetes who were prescribed sodium-glucose cotransporter-2 inhibitors versus other diabetes medications. We found that those taking these drugs had a lower risk of suffering a non-fatal stroke. This finding is important because it suggests that, beyond lowering blood sugar, this class of medications may offer additional protection against stroke, helping patients and doctors make more informed treatment choices.

Details

Publication Type
Journal Article
Journal
Stroke Research and Treatment
Date Published
June 25, 2026
Volume
2026
Issue
1
Pages
6411721
Digital Object Identifier
10.1155/srat/6411721

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